Evidence-Based Nutrition For Chronic Disease Prevention

About Nourished by Science

Here at Nourished by Science, it is our mission to empower people to take charge of their own health by helping them adopt a healthy diet and lifestyle with confidence and clarity.

To this end, we operate this free website and a YouTube channel to share nuanced, evidence-based information about nutrition as it relates to the prevention of chronic disease.

Nourished by Science was founded by Mario Kratz, PhD. Over more than 25 years of conducting clinical nutrition research, Mario met countless individuals who were struggling in one way or another with chronic diseases that were at least partly caused by a poor diet. He has also seen the profound transformations that can result from empowering people to change their lifestyle and particularly their way of eating. 

It is our sincere hope that this website can provide information, motivation, and community to help you minimize your risk of chronic disease so that you can enjoy everything life has to offer.

About Mario Kratz, PhD

Mario holds Master’s and PhD degrees in Nutrition Sciences, both from the University of Bonn in Germany. He completed a postdoctoral fellowship in the Department of Medicine at the University of Washington. A few years later, Mario joined the Fred Hutchinson Cancer Center (or Fred Hutch), also in Seattle, WA, as a faculty member.

Until June of 2021, Mario held the position of Associate Professor in the Cancer Prevention Program, part of the Public Health Sciences Division, at Fred Hutch. He was also a faculty member in the Departments of Epidemiology and Medicine as well as the Nutritional Sciences Program at the University of Washington.

He still holds an appointment as a (non-employee) Affiliate Investigator at Fred Hutch, and continues to be involved in several clinical research projects. However, he is now dedicating the majority of his time to the development of Nourished by Science, with the goal of providing trustworthy, rigorous, and evidence-based information about nutrition, health, and chronic disease to a community of individuals who share his passion for science and a healthy lifestyle.

Mario Kratz

During his tenure in academia, Mario’s laboratory conducted clinical research to investigate the relationship between diet, obesity, and chronic diseases. A major focus of his work was on metabolic diseases such as type 2 diabetes and non-alcoholic fatty liver disease, cardiovascular disease, and cancer. His group was particularly interested in the mechanisms through which diet affects energy homeostasis (i.e., how the body regulates weight and fat mass) and processes that contribute to chronic disease, such as low-grade chronic inflammation, excessive fat accumulation in the liver, or insulin resistance. You can find Mario’s scientific publications on his Google Scholar profile or on his full academic CV.

Mario’s work has been covered in CBS News, Time Magazine, Politico, The Washington Post, Oprah Magazine, The Seattle Times, The Boston Globe, Huffington Post, and The Independent, among others. You can find all links to media coverage of Mario’s work and his public appearances in the section In The News.

As a core faculty member of the Nutrition Sciences Program at the University of Washington, Mario used to regularly mentor students in Master’s and PhD programs in nutrition or epidemiology. He also used to teach a course in Nutritional Epidemiology (NUTR 538 / EPI 538) for many years that focused heavily on the methods used in observational studies and randomized controlled trials. He has served on the editorial board of the American Journal of Clinical Nutrition (AJCN) between 2016 and 2024, and on the editorial board of the Journal of Clinical Endocrinology and Metabolism (JCEM) between 2016 and 2019.

Please note that this website is not related to Mario’s prior employment at Fred Hutch, his prior academic appointments at the University of Washington, or his editorial board activities. All posts are based on our own independent work, and not related in any way to Fred Hutch, the University of Washington, or the American Journal of Clinical Nutrition.

What this Website is All About

Our Goal is to Empower You to Take Care of Your Own Health

When we talk about healthcare these days, it is usually meant as a service that we receive. One of our primary goals is to give you the information, the tools, and the belief that you can be a major player in your own health-care. There is little doubt that nutrition plays a major role in most chronic diseases, and that many are preventable, treatable, or manageable by adopting a healthier diet and lifestyle.

Nourished by Science is Based on Scientific Evidence, Not Diet Tribalism or Dogma

Understanding how the food we eat affects our long-term health is surprisingly difficult to figure out. This field, unfortunately, has a history of drawing conclusions based on fairly poor evidence that later turned out to be at least partly wrong. The resulting back and forth between different diet approaches, each only weakly supported by scientific evidence, has led to confusion about how to eat. As a result, many people have abandoned scientific evidence, with the argument that science hasn’t really provided the answers we need to understand how diet affects long-term health. And that abandonment has led to a rise in diet tribes and pseudo-scientific approaches to eating, superficial views that attribute complex diseases to a single food or dietary factor, and sales pitches for dubious diet programs or supplements. 

We have drawn a very different conclusion from the mistakes of the past. Yes, nutrition science is a difficult science, often forced to work with weak evidence. And yes, the field has often drawn conclusions based on this weak evidence that later had to be revised. However, that does not mean that a non-scientific approach will be more likely to lead us to answers that are truly helpful for our health. It simply means that we need to apply scientific principles more rigorously. This relates to the conduct of the research, but particularly how we interpret and communicate the available data. Our goal at Nourished by Science is to raise the standard of rigor in how we read the scientific literature, the conclusions we draw from it, and the way we communicate the findings.

Doing justice to a complex science means that a real understanding can only be achieved by diving below the surface. All too often, the conversation about certain foods reminds me of the metaphor of the blind men and the elephant. It is easy to make a compelling argument if we focus just on one clear and convincing aspect of a complex issue. So of course the blindfolded person below who stands next to the tail can claim, full of conviction, that what they are dealing with here is a rope, while others are certain that it’s a wall, a snake, or a tube. To figure out the full truth means that they all need to be willing to listen to each other, to consider the entirety of the ‘evidence’, and realize that their one piece of ‘data’ is only a small piece of a complex puzzle.

The blind men and the elephant
The blind men and the elephant

My goal is to look at an issue from all sides and to consider all available evidence. That includes imperfect evidence, anecdotes, ideas, and hypotheses. Oftentimes, plausible ideas are disregarded by the scientific community because no hard evidence exists in the form of randomized controlled trials. I believe this is shortsighted, and that it is important to acknowledge anecdotes, hypotheses, or inconclusive evidence, as long as these are clearly presented as such.

The fact that you found your way to this site suggests that we share a common passion for nutrition and health. More than ever is it clear that nutrition is one of the pillars of health, and in spite of all the problems in this field, there is a lot of reason to feel optimistic about the potential of a proper diet to prevent – and treat – many chronic diseases. We invite you to share your thoughts on any of the content on the site, or share specific experiences with food or diets that seem pertinent. Also, please feel encouraged to contact us if you’d like to see a specific book, paper, or topic covered.

We thank you for being a part of this community.

Nourished by Science Aims to be Independent, Transparent, and Unbiased (as Much as Possible)

Nourished by Science has a policy in place to keep our content free of conflicts of interest.

This means that we will

  • not engage in brand sponsorships with companies in the food, supplement, or pharmaceutical industries;
  • not engage in affiliate marketing of foods, supplements, or nutritional products;
  • not consult for the nutritional, supplement, or pharmaceutical industry; and
  • not accept honoraria, payments, or reimbursements from businesses in, or interests related to, the food, supplement, or pharmaceutical industries.

This policy applies to all employees and contractors of Nourished by Science, and all business activities of Nourished by Science LLC, including but not limited to this website, the Nourished by Science YouTube channel, and our activities on social media.

Last modified: January 14, 2024