Evidence-Based Nutrition For Chronic Disease Prevention

Poster: The Insulin Resistance Syndrome

A Nourished by Science Poster: Download Your Copy Below

The poster helps interpret eight common risk factors for chronic disease that commonly cluster together in the Insulin Resistance Syndrome.

For each risk factor, the optimal level that is associated with the lowest chronic disease risk is shown in the green portion of each bar. The orange portion of each bar indicates a modestly increased risk. And the red portion of each bar shows the level associated with a substantial increase in chronic disease risk.

Below, you can download a free copy of a high-resolution PDF file containing different versions of this poster for men and women of Caucasian (White) or non-White race.

Low resolution image of an example poster for a Caucasian (White) man
Low resolution image of an example poster for a Caucasian (White) man

For more information about the insulin resistance syndrome, please see our dedicated blog post and video about the topic.


The information included in this document is a summary of the scientific evidence demonstrating that elevated waist circumference, elevated fasting triglycerides, elevated blood pressure, elevated fasting glucose, elevated homeostasis model assessment (HOMA) index of insulin resistance, elevated fasting high-sensitivity C-reactive protein, and elevated fasting low-density lipoprotein (LDL) cholesterol as well as low concentrations of high-density lipoprotein (HDL) cholesterol are associated with an increased risk for a variety of chronic diseases. The literature has been interpreted with care, and relevant citations are available on our website.

We provide this document with the understanding that Nourished by Science or its staff cannot assume any responsibility for the correctness or completeness of the information provided herein. 

Please note that our choice of risk factors to include as well as our definition of optimal/low risk, intermediate risk, and elevated risk is subject to interpretation. Other experts and clinicians may decide to include other risk factors, and may define these ranges for low/intermediate/elevated risk differently. 

The document is intended to provide information as to the degree to which different levels of each risk factor are associated with an increased risk of chronic disease. It is not a validated tool for the diagnosis of medical conditions or the assessment of disease risks, does not permit self-diagnosis, and does not constitute medical or dietary advice.

We strongly recommend that any concerns and questions are discussed with a qualified healthcare professional, such as a physician or registered dietitian.

We also specifically recommend using the information only to guide and inform discussions of chronic disease risk with a physician, and in no case to use the information as rationale to terminate or change a prescription medication regimen.